The series focuses on Asta, a young orphan who is left to be raised in an orphanage alongside his fellow orphan, Yuno. While everyone is born with the ability to utilize mana in the form of magical power, Asta, who has no mana and thus no way to use magic, instead focuses on physical strength. Conversely, Yuno was born as a prodigy with immense magical power and the talent to control wind magic.